A ’muscular’ response to regeneration

. Therapies to target neuromuscular disorders affecting million of people worldwide are on the horizon thanks to research at the Montreal Clinical Research Institute of Montreal. CONTENU - Neuromuscular disorders affect millions of people worldwide. Now a discovery made at the Montreal Clinical Research Institute of Montreal (IRCM) opens the door to the development of targeted therapies. Published in the journal Nature Communications, the development caps several years of research by doctoral candidate Viviane Tran under the direction of Université de Montréal medical Jean-François Côté, the IRCM's president and scientific director, with international partners. The formation of muscles, a complex process, requires the action of specialized cells, the myoblasts. In order for skeletal muscle to develop and regenerate, myoblasts must align with each other, move towards each other, and touch each other until their membranes are joined.