A team of University of Calgary researchers is calling it a game-changer for understanding gut health. It has been working on improving 3D models of the human intestine to create more-realistic experiments and tests to help diagnose and treat gastrointestinal issues. Using patient-derived organoids, which are akin to mini-guts, enabled the team to more accurately replicate the internal environment of an intestine on a new gut-on-a-chip platform.

Error loading page resources Please try to reload the page to display it correctly. Consensus on how mindset and surroundings shape therapy outcomes is an important step toward regulatory approval for use of drugs like MDMA and psilocybin in treatment of debilitating mental health conditions As psychedelics gain traction as potential treatments for mental health disorders, an international study led by researchers at McGill University, Imperial College London, and the University of Exeter stands to improve the rigour and reliability of clinical research.

A research project charts the intersection of exposure and vulnerability to gambling to identify high-risk areas and help authorities make informed decisions. The lure of gambling is everywhere: slot machines, casinos, bingo halls, horse racing and lotteries are all'around us. People who are vulnerable to their call are exposed to their physical presence every day.

Vaccination can help prevent infection-related hearing loss in children, but its full potential remains untapped, especially in lowand middle-income countries, a study finds. Over 1.5 billion people worldwide are affected by some degree of hearing loss. While it is often linked to aging, a lesser-known but significant cause is infections contracted during childhood and adolescence, many of which are preventable.

Can clinicians predict how Parkinson's disease or Lewy body dementia will progress in the brain? UdeM medical professor Shady Rahayel looks into the question. At the Centre for Advanced Research in Sleep Medicine (CARSM), at Montreal's Sacré-Coeur Hospital, Université de Montréal medical professor Shady Rahayel sees many patients with REM Sleep Behaviour Disorder (RBD).

In a world first, CRCHUM researcher Martine Tétreault and her team identify a set of biomarkers that could someday make it easy to spot the disease in a patient's blood sample. Parkinson's disease is best known for its effects on the central nervous system. In addition, recent scientific advances generally emphasize the role of the immune system in the presence and development of the disease.

A new study by Marc Therrien's team at the IRIC unravels the mystery of the cancer-causing power of BRAF mutations and identifies novel ways of counteracting them. Researchers led by Université de Montréal pathology and cell-biology professor Marc Therrien have identified major structural changes that enable the BRAF protein to escape control and mimic its activation, giving it strong potential to cause cancer.

Coffee can help you stay awake. But what does caffeine actually do to your brain once you're asleep? Using AI, a team of researchers has an answer: it affects the brain's "criticality". Caffeine is not only found in coffee, but also in tea, chocolate, energy drinks and many soft drinks, making it one of the most widely consumed psychoactive substances in the world.

It happens to the best of us: a week goes by and you haven't found time to get to the gym. Is there any point in making it up on the weekend? A University of Calgary kinesiology researcher offers a resounding - yes! A proof-of-concept study recently dug into how physical activity impacts and benefits your health.

Millions of kidney patients stand to benefit from early diagnosis and prevention thanks to the breakthrough by scientists at the CRCHUM and UdeM. In a world first, Canadian scientists at the CRCHUM, the hospital research centre affiliated with Université de Montréal, have identified microRNA able to protect small blood vessels and support kidney function after severe injury.

A study led by UdeM's Sarah Lippé demonstrates that artificial intelligence can quickly and accurately assess brain maturity in babies, enabling early detection of developmental disorders. Machine-learning algorithms can now estimate the "brain age" of infants with unprecedented precision by analyzing electrical brain signals recorded using electroencephalography (EEG).

Graduating dentist Angélique Thibault believes hypnosis could enhance dental patients' well-being - but first, dentists have to be trained in the technique. Hypnosis could play a significant role in at least three areas of dental care: managing acute pain during dental procedures, reducing the anxiety associated with visiting the dentist, and alleviating chronic orofacial pain.

The growing threat of wildfires in British Columbia and associated health risks are laid bare in two studies from experts at Simon Fraser University. Recent years have seen a dramatic increase in both the number and intensity of wildfires, inflicting unprecedented ecological, social and economic damage, as well as posing severe risks to public health.

An UdeM study examines the effectiveness of giving a special poison to mice to kill the ticks that carry Lyme disease. To fight Lyme disease, you need more than one line of attack. At Université de Montréal's Faculty of Veterinary Medicine, researchers have started using tick poison on mice, which are key hosts for the bacteria responsible for the illness.

Hiding behind numerous disguises, HIV has been evading researchers for years, leaving the search for a vaccine as elusive as the virus itself. Once believed to exist as pure strains or subtypes, new research shows the virus evolves constantly, combining dangerous elements that complicate treatment. As part of its evasive techniques, the virus can lie dormant in cells, avoiding treatments and the body's own immune system.

Western and LHSCRI researchers hope to inform environmental, health policy in high-pollution areas A new study reveals air pollution may contribute to the development of epilepsy, a brain condition that causes seizures. Published in Epilepsia, researchers at London Health Sciences Centre Research Institute (LHSCRI) and Western's Schulich School of Medicine & Dentistry found an association between long-term exposure to air pollution with new cases of epilepsy in adults in Ontario.

Almost all babies who contract the human papillomavirus perinatally eliminate it within the first six months of life - yet even so, women still benefit from protection, a study finds. Nearly all newborns who contract human papillomavirus in the perinatal stage will eliminate the virus in the first six months of life, with very little persistence or recurrence, according to a new Canadian study published today in the Journal of Infectious Disease.

McGill researchers' analysis of online forum conversations finds that some incels offer an ideological rationale for not working or studying, one reinforced by peer pressure The critically acclaimed Netflix drama Adolescence has put a spotlight on the culture and ideas of incels (involuntary celibates), an online subculture of people (mostly male and heterosexual), who define themselves as unable to find a romantic or sexual partner, largely due to their perceived unattractiveness.

Study delved into the social factors that influence whether older adults are able to remain in their homes and communities  While health status is an important factor in whether a person is able to grow old in their home and community (age in place), researchers at McGill University have shed new light on the social factors that can also have an impact, both directly and through their impact on health over a lifetime.

Researchers estimated about 8,500 tonnes of antibiotics end up in river systems each year after passing through the human body and wastewater systems Millions of kilometres of rivers around the world are carrying antibiotic pollution at levels high enough to promote drug resistance and harm aquatic life, a McGill University-led study warns.