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Life Sciences - Health - 31.03.2023
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Life Sciences
Results 1 - 20 of 188.
Loss of key protein could be crucial to understanding ALS: Study
Researchers at the University of Toronto have shown that loss of a key protein in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) may contribute to the underlying cause of both diseases. The protein, known as C9orf72 (C9) and expressed by a gene with the same name, affects movement of molecules between the nucleus and the cytoplasm in the neurons affected in ALS and FTD, the researchers found.
Researchers at the University of Toronto have shown that loss of a key protein in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) may contribute to the underlying cause of both diseases. The protein, known as C9orf72 (C9) and expressed by a gene with the same name, affects movement of molecules between the nucleus and the cytoplasm in the neurons affected in ALS and FTD, the researchers found.
MRNA-based delivery tech for gene editing in the lungs
A team of researchers, including Bowen Li from the University of Toronto's Leslie Dan Faculty of Pharmacy, has developed a new lipid nanoparticle with potential to deliver gene editing tools to cells in the lung - a promising step toward developing new, inhalable therapies for lung diseases such as cystic fibrosis.
A team of researchers, including Bowen Li from the University of Toronto's Leslie Dan Faculty of Pharmacy, has developed a new lipid nanoparticle with potential to deliver gene editing tools to cells in the lung - a promising step toward developing new, inhalable therapies for lung diseases such as cystic fibrosis.
How the brain’s ’internal compass’ works
Scientists have gained new insights into the part of the brain that gives us a sense of direction, by tracking neural activity with the latest advances in brain imaging techniques. The findings shed light on how the brain orients itself in changing environments - and even the processes that can go wrong with degenerative diseases like dementia, that leave people feeling lost and confused.
Scientists have gained new insights into the part of the brain that gives us a sense of direction, by tracking neural activity with the latest advances in brain imaging techniques. The findings shed light on how the brain orients itself in changing environments - and even the processes that can go wrong with degenerative diseases like dementia, that leave people feeling lost and confused.
Co-infection with ’superbug’ bacteria increases SARS-CoV-2 replication
Western study finds co-infection with 'superbug' bacteria increases SARS-CoV-2 replication The study identifies a common protein from the Staphylococcus aureus bacteria boosts SARS-CoV-2 replication up to 15 times By Prabhjot Sohal , March 20, 2023 By Prabhjot Sohal , March 20, 2023 Global data shows nearly 10 per cent of severe COVID-19 cases involve a secondary bacterial co-infection – with Staphylococcus aureus, also known as Staph A.
Western study finds co-infection with 'superbug' bacteria increases SARS-CoV-2 replication The study identifies a common protein from the Staphylococcus aureus bacteria boosts SARS-CoV-2 replication up to 15 times By Prabhjot Sohal , March 20, 2023 By Prabhjot Sohal , March 20, 2023 Global data shows nearly 10 per cent of severe COVID-19 cases involve a secondary bacterial co-infection – with Staphylococcus aureus, also known as Staph A.
Historic logging contributes to water temperature increases for salmon
A collaborative study between researchers at Simon Fraser University and Fisheries and Oceans Canada (DFO) has found that high logging intensity in the Interior watersheds of British Columbia is associated with warmer stream temperatures in salmon-bearing streams, potentially contributing to increased heat stress in salmon.
A collaborative study between researchers at Simon Fraser University and Fisheries and Oceans Canada (DFO) has found that high logging intensity in the Interior watersheds of British Columbia is associated with warmer stream temperatures in salmon-bearing streams, potentially contributing to increased heat stress in salmon.
New study identifies how AI fails to reproduce human vision
Despite the power of deep learning, computers have yet to master human calculations when it comes to visual recognition By Jeff Renaud , March 16, 2023 By Jeff Renaud , March 16, 2023 When a human spots a familiar face or an oncoming vehicle, it takes the brain a mere 100 milliseconds (about one-tenth of a second) to identify it and more importantly, place it in the right context so it can be understood, and the individual can react accordingly.
Despite the power of deep learning, computers have yet to master human calculations when it comes to visual recognition By Jeff Renaud , March 16, 2023 By Jeff Renaud , March 16, 2023 When a human spots a familiar face or an oncoming vehicle, it takes the brain a mere 100 milliseconds (about one-tenth of a second) to identify it and more importantly, place it in the right context so it can be understood, and the individual can react accordingly.
Colorectal cancer and E. coli: new insights
UdeM researchers have found that a lot of healthy people have a gut bacteria implicated in colorectal cancer, and that a popular supplement for promoting digestive health may have the opposite effect. In Quebec, colorectal cancer is the second leading cause of cancer deaths in men and the third in women.
UdeM researchers have found that a lot of healthy people have a gut bacteria implicated in colorectal cancer, and that a popular supplement for promoting digestive health may have the opposite effect. In Quebec, colorectal cancer is the second leading cause of cancer deaths in men and the third in women.
Genes shed light on why men and women experience different depression symptoms
Depression is widely reported to be more common in women than in men, with women twice as likely to receive a diagnosis than men. A new sex-specific study from McGill University has found that there are differences between male and female genes and how they relate to depression. In a study of more than 270,000 individuals, the researchers found that sex-specific prediction methods were more accurate in forecasting an individual's genetic risk of developing depression than prediction methods that did not specify sex.
Depression is widely reported to be more common in women than in men, with women twice as likely to receive a diagnosis than men. A new sex-specific study from McGill University has found that there are differences between male and female genes and how they relate to depression. In a study of more than 270,000 individuals, the researchers found that sex-specific prediction methods were more accurate in forecasting an individual's genetic risk of developing depression than prediction methods that did not specify sex.
Alcohol during pregnancy: drinking too much in the first week is risky
But consuming foods rich in nutrients could counteract some of the negative effects, according to a new Canadian study. CONTENU Serge McGraw, chercheur en épigénétique et spécialiste en biologie de la reproduction au CHU Sainte-Justine Credit: CHU Sainte-Justine Excessive alcohol consumption in the first week of pregnancy poses risks to the unborn child - but having a healthy diet rich in nutrients such as folic acid, vitamin B12, choline and betaine could reduce some of its effects, a new Canadian study reveals.
But consuming foods rich in nutrients could counteract some of the negative effects, according to a new Canadian study. CONTENU Serge McGraw, chercheur en épigénétique et spécialiste en biologie de la reproduction au CHU Sainte-Justine Credit: CHU Sainte-Justine Excessive alcohol consumption in the first week of pregnancy poses risks to the unborn child - but having a healthy diet rich in nutrients such as folic acid, vitamin B12, choline and betaine could reduce some of its effects, a new Canadian study reveals.
Genes reveal kidney cancer’s risk of recurrence
DNA sequencing may provide a more effective way to predict a patient's risk of kidney cancer recurrence and could one day lead to more personalized treatment Studying the mutations in kidney cancer after surgery could help to better predict the risk of the disease coming back, according to the latest results of a decade-long international study.
DNA sequencing may provide a more effective way to predict a patient's risk of kidney cancer recurrence and could one day lead to more personalized treatment Studying the mutations in kidney cancer after surgery could help to better predict the risk of the disease coming back, according to the latest results of a decade-long international study.
A giant step forward in understanding autism
Researchers at the CHU Sainte-Justine Research Centre show that in Fragile X syndrome, the most common cause of autism, sensory signals from the outside world are underrepresented by cortical pyramida Roberto Araya That's the conclusion of a new study by a team led by Université de Montréal neurosciences professor Roberto Araya, a biophysicist and researcher at the UdeM-affiliated CHU Sainte-Justine Research Centre.
Researchers at the CHU Sainte-Justine Research Centre show that in Fragile X syndrome, the most common cause of autism, sensory signals from the outside world are underrepresented by cortical pyramida Roberto Araya That's the conclusion of a new study by a team led by Université de Montréal neurosciences professor Roberto Araya, a biophysicist and researcher at the UdeM-affiliated CHU Sainte-Justine Research Centre.
Is the brain wired differently in people with addictions?
A meta-analysis of neuroimaging studies by Stéphane Potvin points to neurobiological deficits in people with substance abuse problems. CONTENU - Some 10 to 15 per cent of people will have a substance abuse problem at some point in their life, making it one of the most common psychiatric disorders.
A meta-analysis of neuroimaging studies by Stéphane Potvin points to neurobiological deficits in people with substance abuse problems. CONTENU - Some 10 to 15 per cent of people will have a substance abuse problem at some point in their life, making it one of the most common psychiatric disorders.
Chemists create nanomachines by breaking them apart
Some "broken" nanomachines better sense their environment while others gain the ability to control their activity over time, researchers at Université de Montréal find. CONTENU - "Every act of creation," Picasso famously noted, "is first an act of destruction." Taking this concept literally, researchers in Canada have now discovered that "breaking" molecular nanomachines basic to life can create new ones that work even better.
Some "broken" nanomachines better sense their environment while others gain the ability to control their activity over time, researchers at Université de Montréal find. CONTENU - "Every act of creation," Picasso famously noted, "is first an act of destruction." Taking this concept literally, researchers in Canada have now discovered that "breaking" molecular nanomachines basic to life can create new ones that work even better.
New research tool tackles deadly mosquito-borne diseases
For most people living in Canada, mosquitoes are nothing more than a summertime nuisance, intruding on nights at the cottage and evenings around the campfire. But for millions of people around the world, particularly in the Global South, they are a serious and potentially fatal threat.
For most people living in Canada, mosquitoes are nothing more than a summertime nuisance, intruding on nights at the cottage and evenings around the campfire. But for millions of people around the world, particularly in the Global South, they are a serious and potentially fatal threat.
A new understanding of reptile colouration
Snakes and mice don't look alike. But much of what we know about skin colouration and patterning in vertebrates generally, including in snakes, is based on lab mice. However, there are limits to what mice can tell us about other vertebrates because they don't share all of the same types of colour-producing cells, known as chromatophores.
Snakes and mice don't look alike. But much of what we know about skin colouration and patterning in vertebrates generally, including in snakes, is based on lab mice. However, there are limits to what mice can tell us about other vertebrates because they don't share all of the same types of colour-producing cells, known as chromatophores.
Researchers explore gene therapy model using zinc finger proteins
Researchers at the University of Toronto and New York University have developed a novel technology that can engineer proteins to target any stretch of DNA in the human genome, opening a door to gene therapies for a broader range of health conditions.
Researchers at the University of Toronto and New York University have developed a novel technology that can engineer proteins to target any stretch of DNA in the human genome, opening a door to gene therapies for a broader range of health conditions.
New EEG procedure accurately measures distress caused by tinnitus
Researchers discover new way to understand and diagnose patients experiencing ringing in the ears. While it's especially common in older adults, tinnitus - a potentially devastating ringing in the ears - can affect people of all ages. Most often described as consistent buzzing, hissing or humming, tinnitus is usually caused by an underlying condition, like age-related hearing loss, an ear injury or heart disease and affects approximately one in five people in North America.
Researchers discover new way to understand and diagnose patients experiencing ringing in the ears. While it's especially common in older adults, tinnitus - a potentially devastating ringing in the ears - can affect people of all ages. Most often described as consistent buzzing, hissing or humming, tinnitus is usually caused by an underlying condition, like age-related hearing loss, an ear injury or heart disease and affects approximately one in five people in North America.
Colorectal cancer surgery: gut microbiota helps healing
In a promising study, Canadian researchers have shown for the first time in mice that modifying intestinal flora before surgery could reduce postoperative complications in colorectal cancer patients. CONTENU - Published in the journal Gut, the study by scientists at the CHUM Research Centre (CRCHUM) in Montreal identified two bacterial strains that directly affect whether or not anastomotic leakage, more commonly known as intestinal leakage, occurs.
In a promising study, Canadian researchers have shown for the first time in mice that modifying intestinal flora before surgery could reduce postoperative complications in colorectal cancer patients. CONTENU - Published in the journal Gut, the study by scientists at the CHUM Research Centre (CRCHUM) in Montreal identified two bacterial strains that directly affect whether or not anastomotic leakage, more commonly known as intestinal leakage, occurs.
Obesity-related neurodegeneration mimics Alzheimer’s disease
Thinning in the right temporo-parietal cortex and left prefrontal cortex were similar in both groups A new study led by scientists at The Neuro (Montreal Neurological Institute-Hospital) of McGill University finds a correlation between neurodegeneration in obese people and Alzheimer's disease (AD) patients.
Thinning in the right temporo-parietal cortex and left prefrontal cortex were similar in both groups A new study led by scientists at The Neuro (Montreal Neurological Institute-Hospital) of McGill University finds a correlation between neurodegeneration in obese people and Alzheimer's disease (AD) patients.
Moths are the new tool to protect Canada’s wetlands
Waterloo biologists are leading the North American pilot program examining insect-based biocontrol of Phragmites. By Katharine Tuerke Faculty of Science University of Waterloo biologists, in partnership with Agriculture and Agri-Food Canada and the University of Toronto, are leading a North American pilot program that uses moths as a management tool to control an invasive plant threatening Canadian wetlands.
Waterloo biologists are leading the North American pilot program examining insect-based biocontrol of Phragmites. By Katharine Tuerke Faculty of Science University of Waterloo biologists, in partnership with Agriculture and Agri-Food Canada and the University of Toronto, are leading a North American pilot program that uses moths as a management tool to control an invasive plant threatening Canadian wetlands.
Economics - Mar 31
'We're still in the middle of this': Rotman Dean Susan Christoffersen unpacks global banking woes
'We're still in the middle of this': Rotman Dean Susan Christoffersen unpacks global banking woes
Health - Mar 30
Gelareh Zadeh, a neurosurgeon-scientist, recognized with Canada Gairdner Momentum Award
Gelareh Zadeh, a neurosurgeon-scientist, recognized with Canada Gairdner Momentum Award

Environment - Mar 29
'Too comfortable in our own comfort': University of Toronto expert on why we shouldn't waste water
'Too comfortable in our own comfort': University of Toronto expert on why we shouldn't waste water
Social Sciences - Mar 29
Non-Indigenous learners taking up Indigenous languages to support revitalization: CBC Radio
Non-Indigenous learners taking up Indigenous languages to support revitalization: CBC Radio
