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Water pipeline leaks were a big issue in Calgary this past summer , plunging the entire city into two extended periods of water-use restrictions after a mainline suffered a major break in June.

A novel drug molecule could potentially lead to new treatments to prevent Parkinson's disease in younger patients, according to new research. "We are excited about this drug compound because we might have the possibility to develop the first cure for Parkinson's disease, at least for a subset of patients," said lead author  Kalle Gehring , a Professor in the Department of Biochemistry at McGill University and Canada Research Chair in Structural Studies of Neurodegenerative Diseases.

Mathieu Ferron's work sheds light on the cellular mechanisms of insulin resistance in type 2 diabetes, which affects more than 1.2 million Quebecers.

Findings show pharmacists could fill gap in care for people with atrial fibrillation who are at high risk of stroke Atrial fibrillation (Afib) is the most common heart rhythm disorder encountered in clinical practice according to Dr. Roopinder Sandhu, MD, MPH, and the leading cause of stroke in older individuals.

McGill-led research team may have discovered neurological mechanism underlying common eating disorder A McGill University-led research team working in collaboration with a French team (CNRS, INSERM and Sorbonne university) believes it has identified both the neurological mechanism underlying anorexia nervosa as well as a possible cure.

Underrepresented populations have been historically excluded from clinical trials including women, racial and ethnic minority groups, and pregnant, lactating, pediatric and geriatric populations. While the importance of including these groups in clinical trials are slowly being recognized and remedied, there are still questions in how currently prescribed drugs affect these populations, including the safety and efficacy of the medications.

Underrepresented populations have been historically excluded from clinical trials including women, racial and ethnic minority groups, and pregnant, lactating, pediatric and geriatric populations.

Alzheimer's disease is the most common cause of dementia, affecting more than 55 million people worldwide. Currently, the two main approaches for treatments to delay or slow its progression target the buildup of amyloid beta peptides - which form plaques in the spaces between nerve cells in the brain - and the buildup of tau protein, resulting in tangles which damage neurons.

A decade of discovery: how Arnie Charbonneau's generosity sparked momentum and transformed cancer research in Canada A decade after the Arnie Charbonneau Cancer Institute was founded, cutting-edge research discoveries are improving the lives of cancer patients. A candid conversation at a restaurant near the Tom Baker Cancer Centre led to a gift that altered the trajectory of cancer research in Calgary, with impacts across Canada and around the globe.

Canada likely to miss WHO's Hepatitis C elimination target, research shows. Canada will not reach the original World Health Organization's (WHO) target of eliminating the Hepatitis C virus (HCV) by 2030 and lags in comparison to other developed countries, a new study led by researchers at the University of Waterloo has found.

Waterloo student uses mathematical modelling to bring awareness to opioid-related death reduction method Nasal-administered naloxone is more cost-effective and could help reduce the number of opioid-related fatalities compared to the current publicly funded intermuscular version, a new study has found.

UCalgary study finds certain medications decrease diversity and beneficial microorganisms found in the gut, which may affect overall health Our intestines house trillions of microorganisms known as the gut microbiota. These microorganisms are important players in both drug metabolism and certain conditions like high blood pressure, coronary artery disease and diabetes.

Waterloo Pharmacy researchers collaborate with QRxDigital to make prescriptions easier to understand Being able to understand the medications you take should be a given. However, many people struggle to understand what to expect from the medications they're taking and how to take them effectively. Waterloo's clinical associate professor, Dr. Tejal Patel, has teamed up with QRxDigital to include QR codes on medication bottles that link to an instructional video that patients can view at home.

Patented bandage contact lens material could release drugs as needed to help eye abrasions heal faster A cross-disciplinary University of Waterloo team has developed a new contact lens material that could act as a bandage for corneal wounds while releasing drugs in a controlled manner to help the eye heal faster.

UCalgary researchers investigate the science of psilocybin-assisted treatment for alcohol use disorder Clinical trial to explore potential of psychedelics combined with therapy to help someone reduce or stop drinking University of Calgary researchers are about to conduct the largest single-site clinical trial of its kind in Canada to find out whether combining a known therapy with psychedelics could be a viable treatment for alcohol use disorder (AUD).

A new study suggests that a combined vaccine approach could be an effective avenue for preventing severe SARS-CoV-2 infections and reducing transmission of COVID-19. A study led by Dr. Hélène Decaluwe , professor in the Department of Pediatrics at the Université de Montréal and researcher at CHU Sainte-Justine, suggests that a combined approach of intramuscular and mucosal vaccines could be an effective avenue for preventing severe SARS-CoV-2 infections and reducing transmission of COVID-19.

Stéphanie Forté and co-researchers in Canada and Brazil have shown how people with sickle cell disease or sickle cell trait have a higher chance of dying from COVID-19 than the general population. Patients with sickle cell disease and carriers of the sickle cell trait, often considered benign, face higher rates of death and hospitalization if they contract COVID-19, a new Canada-Brazil study suggests.

Researchers at UBC's faculty of medicine are launching a first-of-its-kind clinical trial investigating the potential of cannabidiol (CBD) as a treatment for bipolar depression. Bipolar disorder is a chronic mental health condition characterized by extreme changes in mood that cycle through periods of intense highs (mania) and lows (depression).

Team led by researchers from Western, St. Michael's Hospital and U of T finds deficient vessel repair a major factor A new study involving researchers at Western University, St. Michael's Hospital and University of Toronto has found that South Asians with either heart disease or diabetes had fewer vascular regenerative and reparative cells compared to white European patients.

Researchers design gel from wood pulp to heal damaged heart tissue and improve cancer treatments You can mend a broken heart this Valentine's Day now that researchers invented a new hydrogel that can be used to heal damaged heart tissue and improve cancer treatments. University of Waterloo chemical engineering researcher Dr. Elisabeth Prince teamed up with researchers from the University of Toronto and Duke University to design the synthetic material made using cellulose nanocrystals, which are derived from wood pulp.