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Life Sciences
Results 81 - 100 of 186.
Towards a cure for lymphoma: new research brings hope
UdeM medical professor Tarik Möröy and his team have identified a therapeutic target for the treatment of lymphoma. New light is being shed on the mechanisms underlying the malignant transformation of lymphomas, paving the way for a promising therapeutic target, thanks to research conducted by a team led by Université de Montréal professor Tarik Möröy.
UdeM medical professor Tarik Möröy and his team have identified a therapeutic target for the treatment of lymphoma. New light is being shed on the mechanisms underlying the malignant transformation of lymphomas, paving the way for a promising therapeutic target, thanks to research conducted by a team led by Université de Montréal professor Tarik Möröy.
Cancer drug shows potential as treatment for muscular dystrophy
Science, Health & Technology Brett Goldhawk Researchers at UBC's School of Biomedical Engineering have discovered that an existing cancer drug could have potential as a treatment for muscular dystrophy. The researchers found that the drug - known as a colony-stimulating factor 1 receptor (CSF1R) inhibitor - helped slow the progress of Duchenne muscular dystrophy in mice by increasing the resiliency of muscle fibres.
Science, Health & Technology Brett Goldhawk Researchers at UBC's School of Biomedical Engineering have discovered that an existing cancer drug could have potential as a treatment for muscular dystrophy. The researchers found that the drug - known as a colony-stimulating factor 1 receptor (CSF1R) inhibitor - helped slow the progress of Duchenne muscular dystrophy in mice by increasing the resiliency of muscle fibres.
Combining genetics and brain MRI can aid in predicting chances of Alzheimer’s disease
Simon Fraser researchers are studying how a combination of genetics and brain MRIs may be used to predict the chances of developing Alzheimer's disease in the future. In a newly published study, researchers from SFU-s Functional and Anatomical Imaging & Shape Analysis Lab (FAISAL) identified distinct properties of brain MRIs and genetics that impact the prediction of Dementia of Alzheimer's Type, or DAT, for patients at various stages of the disease, then developed a biomarker that can help predict future conversion to DAT.
Simon Fraser researchers are studying how a combination of genetics and brain MRIs may be used to predict the chances of developing Alzheimer's disease in the future. In a newly published study, researchers from SFU-s Functional and Anatomical Imaging & Shape Analysis Lab (FAISAL) identified distinct properties of brain MRIs and genetics that impact the prediction of Dementia of Alzheimer's Type, or DAT, for patients at various stages of the disease, then developed a biomarker that can help predict future conversion to DAT.
Southern resident killer whales not getting enough to eat since 2018
The endangered southern resident killer whale population isn't getting enough to eat, and hasn't been since 2018, a new UBC study has determined. The animals have been in an energy deficit, averaged across spring, summer and fall, for six of the last 40 years-meaning the energy they get from food is less than what they expend.
The endangered southern resident killer whale population isn't getting enough to eat, and hasn't been since 2018, a new UBC study has determined. The animals have been in an energy deficit, averaged across spring, summer and fall, for six of the last 40 years-meaning the energy they get from food is less than what they expend.
Pre-natal exposure to alcohol: fathers may be partly responsible
In male mice, alcohol consumption in the weeks preceding conception affects the transcription of genes important for fetal development Preventing fetal alcohol spectrum disorder (FASD) has traditionally been seen as a maternal responsibility, but a growing body of research suggests that fathers have a responsibility as well.
In male mice, alcohol consumption in the weeks preceding conception affects the transcription of genes important for fetal development Preventing fetal alcohol spectrum disorder (FASD) has traditionally been seen as a maternal responsibility, but a growing body of research suggests that fathers have a responsibility as well.
Mosquito-repellent paint? Researchers say slippery walls make it difficult for the biting insects to rest
As the planet warms, outbreaks of mosquito-borne diseases are becoming more common around the world. Traditional solutions include bed nets or chemical treatment - but researchers at the University of Toronto's Faculty of Applied Science & Engineering are trying a new angle: mosquito-repellent paint.
As the planet warms, outbreaks of mosquito-borne diseases are becoming more common around the world. Traditional solutions include bed nets or chemical treatment - but researchers at the University of Toronto's Faculty of Applied Science & Engineering are trying a new angle: mosquito-repellent paint.
Researchers and Indigenous students learn about Grand River
Six Nations Polytechnic partners with McMaster University and the University of Waterloo to explore STEM field work in the Grand River By Staff On June 15, grade nine students from Six Nations Polytechnic (SNP) and the STEAM Academy program donned their waders to join researchers Charles de Lannoy , Karen Kidd and Waterloo Biology Professor Mark Servos to conduct experiments in the Grand River.
Six Nations Polytechnic partners with McMaster University and the University of Waterloo to explore STEM field work in the Grand River By Staff On June 15, grade nine students from Six Nations Polytechnic (SNP) and the STEAM Academy program donned their waders to join researchers Charles de Lannoy , Karen Kidd and Waterloo Biology Professor Mark Servos to conduct experiments in the Grand River.
A blueprint for life forms on Mars?
The extremely salty, very cold, and almost oxygen-free environment under the permafrost of Lost Hammer Spring in Canada's High Arctic is the one that most closely resembles certain areas on Mars. So, if you want to learn more about the kinds of life forms that could once have existed - or may still exist - on Mars, this is a good place to look.
The extremely salty, very cold, and almost oxygen-free environment under the permafrost of Lost Hammer Spring in Canada's High Arctic is the one that most closely resembles certain areas on Mars. So, if you want to learn more about the kinds of life forms that could once have existed - or may still exist - on Mars, this is a good place to look.
How does the brain learn?
An international team co-led by UdeM computational neuroscientist Eilif Muller has simulated how synapses in the neocortex change - to better understand how we learn. Everyone knows the human brain is extremely complex - but how does it learn, exactly? Well, the answer may be a lot simpler than commonly believed.
An international team co-led by UdeM computational neuroscientist Eilif Muller has simulated how synapses in the neocortex change - to better understand how we learn. Everyone knows the human brain is extremely complex - but how does it learn, exactly? Well, the answer may be a lot simpler than commonly believed.
AI-powered archaeology draws out hidden evidence of fire use by early humans
Researchers from the University of Toronto, the Weizmann Institute of Science and Hebrew University have identified new evidence of the use of fire by ancient humans at least 800,000 years ago at a site in western Israel. The discovery, described in a study published this week in Proceedings of the National Academy of Sciences , suggests only the sixth location worldwide of evidence of fire more than half a million years old.
Researchers from the University of Toronto, the Weizmann Institute of Science and Hebrew University have identified new evidence of the use of fire by ancient humans at least 800,000 years ago at a site in western Israel. The discovery, described in a study published this week in Proceedings of the National Academy of Sciences , suggests only the sixth location worldwide of evidence of fire more than half a million years old.
Theta waves: a marker of emotional regulation
New findings on theta waves generated in the brain during emotional regulation could lead to more treatment options for disorders such as anxiety and schizophrenia. Without realizing it, we all rely on emotional regulation many times a day. It's the process by which we mitigate the effect of disturbing stimuli in order to stay focused, improve our well-being and respond to demands from our environment.
New findings on theta waves generated in the brain during emotional regulation could lead to more treatment options for disorders such as anxiety and schizophrenia. Without realizing it, we all rely on emotional regulation many times a day. It's the process by which we mitigate the effect of disturbing stimuli in order to stay focused, improve our well-being and respond to demands from our environment.
Regenerating the heart after an attack
Zebrafish are put under the lens at CHU Sainte-Justine Research Centre to see how they repair damaged tissue - with some surprising results. Heart attacks are damaging, and the severity depends on how long blood flow has been interrupted; when temporarily deprived of oxygen, heart cells die. In addition, the heart can't rebuild its own tissue, leading to its failure, the main cause of mortality and morbidity worldwide.
Zebrafish are put under the lens at CHU Sainte-Justine Research Centre to see how they repair damaged tissue - with some surprising results. Heart attacks are damaging, and the severity depends on how long blood flow has been interrupted; when temporarily deprived of oxygen, heart cells die. In addition, the heart can't rebuild its own tissue, leading to its failure, the main cause of mortality and morbidity worldwide.
The secret lives of Darwin’s finches reveal daily commutes the equivalent of 30 soccer fields
Using radio transmitters, scientists have gained new insights into the behaviour of medium ground finches in the Galapagos Islands. A study led by McGill researchers reveals daily movement patterns covering an area equivalent to the size of 30 soccer fields. Until now researchers knew little about the secret lives of these birds, due in part to challenges studying them in their natural habitat, involving rough volcanic rock terrain and harsh climate conditions.
Using radio transmitters, scientists have gained new insights into the behaviour of medium ground finches in the Galapagos Islands. A study led by McGill researchers reveals daily movement patterns covering an area equivalent to the size of 30 soccer fields. Until now researchers knew little about the secret lives of these birds, due in part to challenges studying them in their natural habitat, involving rough volcanic rock terrain and harsh climate conditions.
Canada ranks third worldwide in permeable landscapes for wildlife
Science, Health & Technology Alex Walls Canada ranks third in the world for animal movement between protected areas, finds new UBC research. Researchers created the first global map of where mammals are most likely to move between protected areas, such as national parks and nature reserves. Lead author Dr. Angela Brennan, a research associate at the Institute for Resources, Environment and Sustainability, says she hopes the data will help countries measure their success at protecting biodiversity over time.
Science, Health & Technology Alex Walls Canada ranks third in the world for animal movement between protected areas, finds new UBC research. Researchers created the first global map of where mammals are most likely to move between protected areas, such as national parks and nature reserves. Lead author Dr. Angela Brennan, a research associate at the Institute for Resources, Environment and Sustainability, says she hopes the data will help countries measure their success at protecting biodiversity over time.
Researchers look to unleash the power of stem cells to repair brain injuries
Scientists at the University of Toronto and Sinai Health say they have identified a new way to control the fate of neural stem cells, bringing researchers one step closer to unlocking the mystery of how to repair the brain after injury or stroke. The findings, published recently in the journal Nature Communications , outline a small set of molecules able to keep two major classes of neural stem cells from losing their ability to differentiate into critical components of a mammal's cortex, a part of the brain that controls language and information processing.
Scientists at the University of Toronto and Sinai Health say they have identified a new way to control the fate of neural stem cells, bringing researchers one step closer to unlocking the mystery of how to repair the brain after injury or stroke. The findings, published recently in the journal Nature Communications , outline a small set of molecules able to keep two major classes of neural stem cells from losing their ability to differentiate into critical components of a mammal's cortex, a part of the brain that controls language and information processing.
Researchers unravel a cellular mystery related to salmonella
Salmonella has been at the centre of a scientific riddle that's puzzled researchers for more than 20 years. The pathogen is well known for causing food-borne illnesses and can infect people through contaminated food or water. But until recently, no one knew how the microbe - strains of which can also cause typhoid fever and post-infectious arthritis - manipulates a fundamental class of cellular lipids called phosphoinositides.
Salmonella has been at the centre of a scientific riddle that's puzzled researchers for more than 20 years. The pathogen is well known for causing food-borne illnesses and can infect people through contaminated food or water. But until recently, no one knew how the microbe - strains of which can also cause typhoid fever and post-infectious arthritis - manipulates a fundamental class of cellular lipids called phosphoinositides.
Where are the next zoonotic viruses lurking?
A research team has used AI to produce a list of animal viruses that could jump the species barrier and cause infections in humans. Until recently, we knew of only two percent of the possible interactions between mammals and viruses, or the "virome." However, a new artificial intelligence (AI) technique has identified potential new host-virus interactions, increasing the size of the known virome by a factor of 15.
A research team has used AI to produce a list of animal viruses that could jump the species barrier and cause infections in humans. Until recently, we knew of only two percent of the possible interactions between mammals and viruses, or the "virome." However, a new artificial intelligence (AI) technique has identified potential new host-virus interactions, increasing the size of the known virome by a factor of 15.
Two pathogens linked to salmon health and survival in B.C
Science, Health & Technology Lou Corpuz-Bosshart Many wild salmon populations in B.C. have experienced substantial declines over the last three decades. New UBC research published today can help chart a course towards better protection of wild salmon. The study, led by UBC faculty of forestry member Arthur Bass and using data generated by the Strategic Salmon Health Initiative , assessed dozens of pathogens in thousands of Chinook and Coho salmon sampled over a decade along the B.C. coast.
Science, Health & Technology Lou Corpuz-Bosshart Many wild salmon populations in B.C. have experienced substantial declines over the last three decades. New UBC research published today can help chart a course towards better protection of wild salmon. The study, led by UBC faculty of forestry member Arthur Bass and using data generated by the Strategic Salmon Health Initiative , assessed dozens of pathogens in thousands of Chinook and Coho salmon sampled over a decade along the B.C. coast.
New insights on link between genetic mutations and biological evolution
From the longer-beaked Galapagos Island finches studied by biologist Charles Darwin - which enabled them to more effectively snatch insects - to the ability of some humans over others to digest milk, genetic differences that give organisms a competitive edge drive the process of natural selection. Now, research by Alex N. Nguyen Ba , an assistant professor of biology at the University of Toronto Mississauga, adds an important dimension to our understanding of how genes interact in the evolutionary process.
From the longer-beaked Galapagos Island finches studied by biologist Charles Darwin - which enabled them to more effectively snatch insects - to the ability of some humans over others to digest milk, genetic differences that give organisms a competitive edge drive the process of natural selection. Now, research by Alex N. Nguyen Ba , an assistant professor of biology at the University of Toronto Mississauga, adds an important dimension to our understanding of how genes interact in the evolutionary process.
Research duo brings breakthrough research to Western
Dr. Xiao Zhen Zhou (left) and Dr. Kun Ping Lu recently joined Western's Schulich Medicine and Dentistry from Harvard University. (credit: Schulich Medicine and Dentistry) Scientists Drs. Kun Ping Lu and Xiao Zhen Zhou are navigating a delicate balancing act. They are studying a stress response enzyme involved in a puzzling inverse relationship between cancer and Alzheimer's disease: People at risk for one disease are less likely to get the other.
Dr. Xiao Zhen Zhou (left) and Dr. Kun Ping Lu recently joined Western's Schulich Medicine and Dentistry from Harvard University. (credit: Schulich Medicine and Dentistry) Scientists Drs. Kun Ping Lu and Xiao Zhen Zhou are navigating a delicate balancing act. They are studying a stress response enzyme involved in a puzzling inverse relationship between cancer and Alzheimer's disease: People at risk for one disease are less likely to get the other.
Research management - Mar 27
University of Toronto scores top marks in QS World University Rankings by Subject
University of Toronto scores top marks in QS World University Rankings by Subject

Event - Mar 27
In photos: New Canadians take citizenship oath at University of Toronto Mississauga-hosted ceremony
In photos: New Canadians take citizenship oath at University of Toronto Mississauga-hosted ceremony
