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Researchers at the IRCM discover that blocking the CD200R1 molecule in mice activates certain immune cells called macrophages, helping to eliminate blood cancers from their bodies. Immunotherapy has revolutionized cancer treatment by mobilizing the immune system to attack tumour cells. Major advances, such as immune checkpoint inhibitors (notably against the PD-1 protein), have produced impressive results against certain types of cancer, including melanoma and kidney cancer.

A groundbreaking clinical trial led by London Health Sciences Centre Research Institute (LHSCRI) and Western's Schulich School of Medicine & Dentistry may enhance how medical professionals detect hidden blood clots responsible for strokes. The study, published in The Lancet Neurology , is the first to show that extending imaging to include the heart within minutes of a patient's arrival to hospital with an acute stroke significantly improves the ability to determine the stroke's underlying cause.

UCalgary research team discovers novel method for transforming limestone into a bacteria-killing nanoparticle Researchers at the University of Calgary have teamed up with an Alberta-based company to turn limestone into a long-lasting antimicrobial agent, a discovery that could help to cut the spread of harmful bacteria and fungi in food and health-care settings.

UdeM's veterinarians reveal that anxiety plays a key role in feline idiopathic cystitis, an inflammation of the bladder, highlighting the importance of reducing the stress that cats sometimes feel. Are recurring bouts of cystitis in cats linked to stress? Yes, indeed, according to a study of 33 cats by a behavioural medicine team at the CHUV, the animal hospital of Université de Montréal's Faculty of Veterinary Medicine.

This article takes stock of a vast international project, under the scientific direction of Walter Wittich, to define the biopsychosocial criteria for deafblindness What is deafblindness? More than the addition of two handicaps, deafblindness creates very specific challenges, since the loss of one sense is difficult to compensate for by another.

An interdisciplinary study draws on interviews with Dominicans displaced by Hurricane Maria and Tropical Storm Erika to explore the risks associated with climate change in the Caribbean. A container was blown away by the force of the winds (Hurricane Maria) and is blocking the entrance to the Hospital in Portsmouth (North of Dominica) Credit: Patrick Cloos In September 2017, Hurricane Maria ripped through the Caribbean, devastating the small island nation of Dominica in the Lesser Antilles, between Guadeloupe and Martinique.

A team of University of Calgary researchers is calling it a game-changer for understanding gut health. It has been working on improving 3D models of the human intestine to create more-realistic experiments and tests to help diagnose and treat gastrointestinal issues. Using patient-derived organoids, which are akin to mini-guts, enabled the team to more accurately replicate the internal environment of an intestine on a new gut-on-a-chip platform.

Error loading page resources Please try to reload the page to display it correctly. Consensus on how mindset and surroundings shape therapy outcomes is an important step toward regulatory approval for use of drugs like MDMA and psilocybin in treatment of debilitating mental health conditions As psychedelics gain traction as potential treatments for mental health disorders, an international study led by researchers at McGill University, Imperial College London, and the University of Exeter stands to improve the rigour and reliability of clinical research.

A research project charts the intersection of exposure and vulnerability to gambling to identify high-risk areas and help authorities make informed decisions. The lure of gambling is everywhere: slot machines, casinos, bingo halls, horse racing and lotteries are all'around us. People who are vulnerable to their call are exposed to their physical presence every day.

Vaccination can help prevent infection-related hearing loss in children, but its full potential remains untapped, especially in lowand middle-income countries, a study finds. Over 1.5 billion people worldwide are affected by some degree of hearing loss. While it is often linked to aging, a lesser-known but significant cause is infections contracted during childhood and adolescence, many of which are preventable.

Can clinicians predict how Parkinson's disease or Lewy body dementia will progress in the brain? UdeM medical professor Shady Rahayel looks into the question. At the Centre for Advanced Research in Sleep Medicine (CARSM), at Montreal's Sacré-Coeur Hospital, Université de Montréal medical professor Shady Rahayel sees many patients with REM Sleep Behaviour Disorder (RBD).

In a world first, CRCHUM researcher Martine Tétreault and her team identify a set of biomarkers that could someday make it easy to spot the disease in a patient's blood sample. Parkinson's disease is best known for its effects on the central nervous system. In addition, recent scientific advances generally emphasize the role of the immune system in the presence and development of the disease.

A new study by Marc Therrien's team at the IRIC unravels the mystery of the cancer-causing power of BRAF mutations and identifies novel ways of counteracting them. Researchers led by Université de Montréal pathology and cell-biology professor Marc Therrien have identified major structural changes that enable the BRAF protein to escape control and mimic its activation, giving it strong potential to cause cancer.

It happens to the best of us: a week goes by and you haven't found time to get to the gym. Is there any point in making it up on the weekend? A University of Calgary kinesiology researcher offers a resounding - yes! A proof-of-concept study recently dug into how physical activity impacts and benefits your health.

Millions of kidney patients stand to benefit from early diagnosis and prevention thanks to the breakthrough by scientists at the CRCHUM and UdeM. In a world first, Canadian scientists at the CRCHUM, the hospital research centre affiliated with Université de Montréal, have identified microRNA able to protect small blood vessels and support kidney function after severe injury.

An UdeM study examines the effectiveness of giving a special poison to mice to kill the ticks that carry Lyme disease. To fight Lyme disease, you need more than one line of attack. At Université de Montréal's Faculty of Veterinary Medicine, researchers have started using tick poison on mice, which are key hosts for the bacteria responsible for the illness.

Hiding behind numerous disguises, HIV has been evading researchers for years, leaving the search for a vaccine as elusive as the virus itself. Once believed to exist as pure strains or subtypes, new research shows the virus evolves constantly, combining dangerous elements that complicate treatment. As part of its evasive techniques, the virus can lie dormant in cells, avoiding treatments and the body's own immune system.

Western and LHSCRI researchers hope to inform environmental, health policy in high-pollution areas A new study reveals air pollution may contribute to the development of epilepsy, a brain condition that causes seizures. Published in Epilepsia, researchers at London Health Sciences Centre Research Institute (LHSCRI) and Western's Schulich School of Medicine & Dentistry found an association between long-term exposure to air pollution with new cases of epilepsy in adults in Ontario.

Almost all babies who contract the human papillomavirus perinatally eliminate it within the first six months of life - yet even so, women still benefit from protection, a study finds. Nearly all newborns who contract human papillomavirus in the perinatal stage will eliminate the virus in the first six months of life, with very little persistence or recurrence, according to a new Canadian study published today in the Journal of Infectious Disease.

Study delved into the social factors that influence whether older adults are able to remain in their homes and communities  While health status is an important factor in whether a person is able to grow old in their home and community (age in place), researchers at McGill University have shed new light on the social factors that can also have an impact, both directly and through their impact on health over a lifetime.